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KMID : 0364020040370070606
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Korean Journal of Thoracic and Cardiovascular Surgery
2004 Volume.37 No. 7 p.606 ~ p.608
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Protamine Induced Anaphylactic Reaction after Cardiopulmonary Bypass -A case report-
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백종현/Baek JH
이동협/한승세/이정철/정태은/이장훈/Lee DH/Han SS/Lee JC/Jung TE/Lee JH
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Abstract
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Anaphylactic reaction to protamine sulfate, which is used widely to reverse the anticoagulative effect of heparin after cardiopulmonary bypass, is very rare. But the result of anaphylactic reaction can be very fatal and the mechanism of it is still not clear. We report a case of severe anaphylactic reaction to protamine sulfate following the replacement of the mitral valve and Maze procedure using microwave in a non-diabetic 57-year-old female patient. (Korean J Thorac Cardiovasc Surg 2004;37:606-608)
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